Tokyo, Japan (Dec. 22, 2005)

We are pleased to announce the formation of the recent partnership between ProPharma Partners and Biolink International.

ProPharma Partners, with offices in London and the San Francisco Bay area in California, and Biolink International, Inc., with offices in Tokyo and Pennsylvania, provide extensive business development and strategic advisory expertise at the local, regional and/or global level in the major pharmaceutical markets of Japan & Asia, Europe and North America.

This new partnership expands the breadth of services and global reach ProPharma Partners and Biolink International are able to provide to the pharmaceutical and biotechnology industries. Client companies who engage ProPharma or Biolink can expand access to the expertise and contacts of ProPharma and Biolink globally.

ProPharma Partners and Biolink International have an extensive record of successfully providing a range of services which include:

• Product and technology in-licensing/ out-licensing and acquisitions
• Strategic business and product development consulting
• Business and product due diligence and valuation modeling
• A virtual team of individuals with expertise in preclinical, pharmacokinetics, CMC, clinical and regulatory affairs to assist in defining and implementing drug development plans.

About Biolink International

Biolink International, Inc. is a Japan-based consulting firm that provides specialized services and solutions to pharmaceutical firms, bio-venture firms in the pre- and post-IPO stages, and technology-based firms that aim to expand strategic partnerships and alliances in Japan for business growth and global coverage. Biolink International, Inc. offers services in the following healthcare related areas:

• Biopharmaceuticals
• Diagnostics and their systems
• Bio-materials for clinical use
• Technology services for the new drug discovery

About ProPharma Partners

ProPharma Partners Inc. provides extensive business consulting and drug development expertise to early stage and established biopharmaceutical companies. ProPharma Partners specializes in assisting companies plan and implement strategic, business and product development initiatives. With offices in Hayward, California, London, Tokyo and Taipei, ProPharma Partners has the expertise and the capability to facilitate technology and product development transactions among US, European and Japanese companies.

The global reach of ProPharma Partners provides client companies a truly international source of expertise to assist in navigating through cultural, legal and language differences in order to achieve their international pharmaceutical and business development objectives. For further information, visit www.propharmapartners.com